{"id":8076,"date":"2025-03-26T09:06:11","date_gmt":"2025-03-26T08:06:11","guid":{"rendered":"https:\/\/esthetic.sk\/blog-en\/mounjaro-saxenda-ozempic-what-is-the-difference-between-them-and-which-is-the-best\/"},"modified":"2026-11-12T18:29:31","modified_gmt":"2026-11-12T17:29:31","slug":"mounjaro-saxenda-ozempic-what-is-the-difference-between-them-and-which-is-the-best","status":"publish","type":"post","link":"https:\/\/esthetic.sk\/en\/blog-en\/mounjaro-saxenda-ozempic-what-is-the-difference-between-them-and-which-is-the-best\/","title":{"rendered":"Wegovy, Mounjaro, Saxenda, Ozempic &#8211; about modern slimming drugs. What is the difference between them and which is the best?"},"content":{"rendered":"  <p>In recent years, there has been more and more talk about modern drugs for weight loss and the treatment of type 2 diabetes. Among the most frequently mentioned are <b>Wegovy<\/b>, <b>Mounjaro<\/b>, <b>Saxenda<\/b> and <b>Ozempic<\/b>. Each has a slightly different composition, effect and approved use. What is the difference between them and which one is available and suitable in Slovakia?    <\/p>\r\n\r\n  <h2>1. Wegovy (semaglutide)<\/h2>\r\n  <p><b>Wegovy<\/b> is a medicine from Novo Nordisk intended for reducing body weight and maintaining the weight loss achieved. It contains <b>semaglutide<\/b>, which acts on GLP-1 receptors, helps reduce hunger, increase satiety and limit food intake. Ozempic, which is intended for the treatment of type 2 diabetes, contains the same active substance.<\/p>\r\n  <ul>\r\n    <li><b>High efficacy:<\/b> in the STEP UP clinical trial, Wegovy at a dose of 7.2 mg achieved an average body weight reduction of <b>20.7%<\/b>, provided the treatment was followed without interruption or change. Roughly one in three patients in the trial lost <b>25% or more<\/b> of their body weight.<\/li>\r\n    <li><b>Availability in Slovakia:<\/b> it is currently available on prescription in our clinic Esthetic<\/li>\r\n  <\/ul>\r\n  <p>Source: <a href=\"https:\/\/www.appliedclinicaltrialsonline.com\/view\/step-up-trial-semaglutide-superior-weight-loss\" target=\"_blank\" rel=\"noopener\">Applied Clinical Trials, STEP UP trial results<\/a><\/p>\r\n\r\n  <h2>2. Mounjaro (tirzepatide)<\/h2>\r\n  <p><b>Mounjaro<\/b> is a relatively new drug developed by Eli Lilly. Its active ingredient is <b>tirzepatide<\/b>, which acts on two hormones: GLP-1 and GIP. This increases satiety, reduces appetite and also improves blood sugar control.   Application 1x per week.  <\/p>\r\n  <ul>\r\n   \r\n    <li><b>Major benefit:<\/b> significant weight loss (more than 20% of body weight in clinical studies)<\/li>\r\n    <li><b>Availability in Slovakia:<\/b> it is currently available on prescription in our clinic Esthetic<\/li>\r\n  <\/ul>\r\n\r\n  <h2>3. Saxenda (liraglutide)<\/h2>\r\n  <p><b>Saxenda<\/b> is a <b>liraglutide-based<\/b> drug that is approved <b>directly for weight loss<\/b>, not diabetes. Its effect is to mimic the hormone GLP-1, which regulates appetite and slows gastric emptying. <\/p>\r\n  <ul>\r\n    \r\n    <li><b>Daily administration:<\/b> injection once a day<\/li>\r\n    <li><b>Availability in Slovakia:<\/b> yes, on prescription<\/li>\r\n  <\/ul>\r\n\r\n  <h2>4. Ozempic (semaglutide)<\/h2>\r\n  <p><b>Ozempic<\/b> is mainly known as a treatment for type 2 diabetes, but it has also quickly gained popularity for its weight loss effects. Like Saxenda, it works via GLP-1, but has a longer half-life and is only given <b>once a week<\/b>.  <\/p>\r\n  <ul>\r\n    \r\n    <li><b>Side effect:<\/b> significant weight reduction<\/li>\r\n    <li><b>Availability in Slovakia:<\/b> yes, on prescription (primarily for diabetics)<\/li>\r\n  <\/ul>\r\n\r\n  <h2>Which is the best?<\/h2>\r\n  <p>It depends on what you need:<\/p>\r\n  <ul>\r\n    <li><b>For significant weight loss:<\/b> Wegovy and Mounjaro have the greatest potential.<\/li>\r\n    <li><b>For legally approved weight loss:<\/b> Saxenda is a drug approved <b>for weight loss only<\/b>.<\/li>\r\n    <li><b>For the combination of diabetes and weight loss:<\/b> Ozempic is a very popular choice.<\/li>\r\n  <\/ul>\r\n\r\n  \r\n\r\n  <h2>The best way to reduce weight<\/h2>\r\n  <p>Make an appointment for a consultation and examination by a physician to determine the best way for you to lose weight.<\/p> \r\n  \r\n <p>For more information on <a href=\"https:\/\/esthetic.sk\/en\/preventive-medicine\/treatment-of-excess-weight-and-obesity\/\">overweight and obesity treatment, click here.<\/a><\/p>\r\n  \r\n  <div id=\"objednavka\" style=\"text-align: center; 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